6850(6850克等于多少斤)

Official Full Name
spleen associated tyrosine kinase
Primary source
HGNC:HGNC:11491
See related
MIM:600085; AllianceGenome:HGNC:11491
Gene type
protein coding
6850
RefSeq status
REVIEWED
Organism
Lineage
Also known as
IMD82; p72-Syk
Summary
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein 6850 is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Expression
Broad expression in lymph node (RPKM 32.4), appendix (RPKM 24.8) and 20 other tissues See more
Orthologs
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九幽软件 » 6850(6850克等于多少斤)